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1.
PNAS Nexus ; 2(5): pgad142, 2023 May.
Article in English | MEDLINE | ID: covidwho-20236372

ABSTRACT

Classrooms are high-risk indoor environments, so analysis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission in classrooms is important for determining optimal interventions. Due to the absence of human behavior data, it is challenging to accurately determine virus exposure in classrooms. A wearable device for close contact behavior detection was developed, and we recorded >250,000 data points of close contact behaviors of students from grades 1 to 12. Combined with a survey on students' behaviors, we analyzed virus transmission in classrooms. Close contact rates for students were 37 ± 11% during classes and 48 ± 13% during breaks. Students in lower grades had higher close contact rates and virus transmission potential. The long-range airborne transmission route is dominant, accounting for 90 ± 3.6% and 75 ± 7.7% with and without mask wearing, respectively. During breaks, the short-range airborne route became more important, contributing 48 ± 3.1% in grades 1 to 9 (without wearing masks). Ventilation alone cannot always meet the demands of COVID-19 control; 30 m3/h/person is suggested as the threshold outdoor air ventilation rate in a classroom. This study provides scientific support for COVID-19 prevention and control in classrooms, and our proposed human behavior detection and analysis methods offer a powerful tool to understand virus transmission characteristics and can be employed in various indoor environments.

2.
17th International Conference on Indoor Air Quality and Climate, INDOOR AIR 2022 ; 2022.
Article in English | Scopus | ID: covidwho-2324929

ABSTRACT

COVID-19 has threatened human lives. However, the efficiency of combined interventions on COVID-19 has not been accurately analyzed. In this study, an improved SEIR model considering both real human indoor close contact behaviors and personal susceptibility to COVID-19 was established. Taking Hong Kong as an example, a quantitative efficiency assessment of combined interventions (i.e. close contact reduction, vaccination, mask-wearing, school closures, workplace closures, and body temperature screening in public places) was carried out. The results showed that the infection risk of COVID-19 of students, workers, and non-workers/students were 3.1%, 8.7%, and 13.6%, respectively. The basic reproduction number R0 was equal to 1 when the close contact reduction rate was 59.9% or the vaccination rate reached 89.5%. The results could provide scientific support for interventions on COVID-19 prevention and control. © 2022 17th International Conference on Indoor Air Quality and Climate, INDOOR AIR 2022. All rights reserved.

3.
J Med Syst ; 47(1): 54, 2023 May 02.
Article in English | MEDLINE | ID: covidwho-2313690

ABSTRACT

From 6 Jan 22 to 17 Feb 22, a total of 729,367 close contacts classified into four distinct groups (i.e., household, social, school and nursing/ welfare home contacts) were managed by the Health Risk Warning system. High COVID-19-positive rates were demonstrated amongst household contacts, i.e., 10.9% (37,220/342,302) were detected via antigen rapid test kits and 56.5% (4,952/8,767) were detected via polymerase chain reaction testing. Household contacts represent the highest risk of being infected by virtue of the sustained close-proximity interactions in the household setting. Social, school and nursing/ welfare home contacts continue to remain at-risk groups for close monitoring. At a population level, household and symptomatic close contacts should be the groups of focus in the early phases of the pandemic, including future potential waves involving COVID-19 variants of concern.


Subject(s)
COVID-19 , Humans , COVID-19/epidemiology , SARS-CoV-2 , Contact Tracing , Pandemics
4.
Journal of Health Sciences and Surveillance System ; 11(1 S):156-163, 2023.
Article in English | Scopus | ID: covidwho-2300142

ABSTRACT

Background: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) can be transmitted through direct, indirect, or close contact with infected people by contaminated respiratory droplets or saliva. This study aimed to investigate the epidemiology of coronavirus disease 2019 (COVID-19) and the secondary attack rate (SAR) in the cases' close contact. Methods: A total of 431 confirmed COVID-19 patients were randomly selected using systematic random sampling from 15 May to 13 June 2020. The required data were extracted from the CORONALAB database of the Center for Disease Control and Prevention (CDC) at Shiraz University of Medical Sciences. Detection of COVID-19 was performed using Real-Time Polymerase Chain Reaction (RT-PCR) and nasopharyngeal swabs. SAR was also calculated for different groups. Results: Among the index cases, 64.27% were male, 24.80% were public sector employees, and 4.87% were admitted to the intensive care unit. In addition, most of them aged 30-39 years. The SAR was 11.56% (95% CI: 9.86% to 13.25%) in the close contacts. Accordingly, the highest SAR was observed among the friends, 19.05% (95% CI: 7.17% to 30.92%), followed by the spouses of COVID-19 cases, 16.67% (95% CI: 10.81% to 22.51%). Furthermore, diabetes (6.03%) and cardiovascular disease (5.1%) were the most common comorbidities among the index cases. Conclusion: The findings suggested that the SAR was relatively lower among the close contacts. Considering the familial and non-familial relationships between the index cases and their close contacts were the major causes of disease transmission. Therefore, it is crucial to conduct tracing for COVID-19 contacts in all cases with whom patients have had close contact. © 2023 Authors. All rights reserved.

5.
KSII Transactions on Internet and Information Systems ; 17(2):644-662, 2023.
Article in English | Scopus | ID: covidwho-2298887

ABSTRACT

There are still outbreaks of COVID-19 across the world. Ships increase the risk of worldwide transmission of the virus. Close contact tracing remains as an effective method of reducing the risk of virus transmission. Therefore, close contact tracing in ship environments becomes a research topic. Exposure Notifications API (Application Programming Interface) can be used to determine the encountered location points of close contacts on ships. Location points of close contact are estimated by the encountered location points. Risky areas in ships can be calculated based on the encountered location points. The tracking of close contacts is possible with Bluetooth technology without the Internet. The Bluetooth signal can be used to judge the proximity among detecting devices by using the feature that Bluetooth has a strong signal at close range. This Bluetooth feature makes it possible to trace close contacts in ship environments. In this paper, we propose a method for close contact tracing and showing the risky area in a ship environment by combining beacon and Exposure Notification API using Bluetooth technology. This method does not require an Internet connection for tracing close contacts and can protect the personal information of close contacts. Copyright © 2023 KSII.

6.
Build Simul ; 16(5): 765-780, 2023.
Article in English | MEDLINE | ID: covidwho-2293290

ABSTRACT

During the Coronavirus disease 2019 pandemic, short-range virus transmission has been observed to have a higher risk of causing infection than long-range virus transmission. However, the roles played by the inhalation and large droplet routes cannot be distinguished in practice. A recent analytical study revealed the predominance of short-range inhalation over the large droplet spray route as causes of respiratory infections. In the current study, short-range exposure was analyzed via computational fluid dynamics (CFD) simulations using a discrete phase model. Detailed facial membranes, including eyes, nostrils, and a mouth, were considered. In CFD simulations, there is no need for a spherical approximation of the human head for estimating deposition nor the "anisokinetic aerosol sampling" approximation for estimating inhalation in the analytical model. We considered two scenarios (with two spheres [Scenario 1] and two human manikins [Scenario 2]), source-target distances of 0.2 to 2 m, and droplet diameters of 3 to 1,500 µm. The overall CFD exposure results agree well with data previously obtained from a simple analytical model. The CFD results confirm the predominance of the short-range inhalation route beyond 0.2 m for expiratory droplets smaller than 50 µm during talking and coughing. A critical droplet size of 87.5 µm was found to differentiate droplet behaviors. The number of droplets deposited on the target head exceeded those exposed to facial membranes, which implies a risk of exposure through the immediate surface route over a short range. Electronic Supplementary Material ESM: the Supplementary Materials are available in the online version of this article at 10.1007/s12273-022-0968-y.

7.
Clin Pediatr (Phila) ; : 99228221124662, 2022 Oct 02.
Article in English | MEDLINE | ID: covidwho-2301849

ABSTRACT

OBJECTIVE: To analyze clinical differences between a pediatric population with and without confirmed positive close contact for the new coronavirus, to establish the symptoms that define a population currently served in a children's emergency room for which polymerase chain reaction (PCR) collection for SARS-COV-2 is performed, and thus, make clinical and laboratory screening more reliable and applicable in medical routine. METHOD: Cross-sectional study that characterized 128 children (0-17 years old) who collected PCR for SARS-COV-2 when seen in an emergency room at a private hospital between March and June 2020. Data were collected from the electronic medical record of the researched hospital. RESULTS: Patients positive for close contact with COVID-19 had more diarrhea (P = .03) and less fever (P = .003) and coughing (P = .03). There was no statistically significant difference between the 2 groups on gender distribution, age, isolation of other etiologic agents, chest x-ray abnormalities, or the need for hospitalization. SARS-Cov-2 PCR showed a higher positivity among patients on the close contact positive group (P < .001). CONCLUSION: As seen in previous research, positive SARS-CoV-2 tests are not required for the pediatric population to be diagnosed with the new coronavirus. Diarrhea should be included in those related to a high suspicion of potential SARS-CoV-2 infection, prompting nasopharyngeal PCR collection. However, fever and cough are unspecific symptoms for SARS-CoV-2 infection and should not be considered as warning signs for parents and, more importantly, for pediatricians to collect screening examinations.

8.
Tokyo Jikeikai Medical Journal ; 68(1):1-7, 2021.
Article in English | EMBASE | ID: covidwho-2263206

ABSTRACT

Objective: We evaluated patients suspected or confirmed to have coronavirus disease 2019 (COVID- 19) to determine predictive factors for the diagnosis of COVID- 19. Method(s): We conducted a retrospective cohort study at The Jikei University Hospital, Tokyo, Japan. This study included adult patients who underwent medical examination for suspected or confirmed COVID- 19 in April and May 2020. We analyzed the clinical characteristics, blood test results, and findings of computed tomography of the chest from the medical record system of the hospital. Result(s): Of the 267 patients included in this study, 27 were found to be positive for COVID- 19 on reverse transcription polymerase chain reaction testing for severe acute respiratory syndrome coronavirus 2 (SARS- CoV- 2). Of the patients, 128 (47.9%) were men, and the median age was 47 years (interquartile range, 34.5- 65). Twenty- two (8.2%) patients had a history of close contact with a COVID- 19 patient. The most common symptoms were fever, general malaise, and cough. Multivariate analysis with the logistic regression model revealed that close contact, fever for 4 or more days, dysgeusia, and dysosmia were independent predictive factors for reverse transcription polymerase chain reaction test results being positive for SARS- CoV- 2. Conclusion(s): Patients who have had close contact with a COVID- 19 patient, fever for 4 days or more, dysgeusia, or dysosmia should undergo diagnostic testing for SARS- CoV- 2.Copyright © 2021 Jikei University School of Medicine. All rights reserved.

9.
IJID Reg ; 7: 22-30, 2023 Jun.
Article in English | MEDLINE | ID: covidwho-2264076

ABSTRACT

Objective: The aim of this study was to observe the secondary infection rate and transmission dynamics of COVID-19 among household contacts, and their associations with various factors across four dimensions of interaction. Methods: This was a case-ascertained study among unvaccinated household contacts of a laboratory-confirmed COVID-19 case in New Delhi between December 2020 and July 2021. For this study, 99 index cases and their 316 household contacts were interviewed and sampled (blood and oro-nasal swab) on days 1, 7, 14, and 28. Results: The secondary infection rate among unvaccinated household contacts was 44.6% (95% confidence interval (CI) 39.1-50.1). The predictors of secondary infection among individual contact levels were: being female (odds ratio (OR) 2.13), increasing age (OR 1.01), symptoms at baseline (OR 3.39), and symptoms during follow-up (OR 3.18). Among index cases, age of the primary case (OR 1.03) and symptoms during follow-up (OR 6.29) were significantly associated with secondary infection. Among household-level and contact patterns, having more rooms (OR 4.44) and taking care of the index case (OR 2.02) were significantly associated with secondary infection. Conclusion: A high secondary infection rate highlights the need to adopt strict measures and advocate COVID-19-appropriate behaviors. A targeted approach for higher-risk household contacts would efficiently limit infections among susceptible contacts.

10.
Building and Environment ; 229, 2023.
Article in English | Scopus | ID: covidwho-2246284

ABSTRACT

To quantify the risk of the transmission of respiratory infections in indoor environments, we systematically assessed exposure to talking- and breathing-generated respiratory droplets in a generic indoor environment using computational fluid dynamic (CFD) simulations. The flow field in the indoor environment was obtained with SST k-ω model and Lagrangian method was used to predict droplet trajectories, where droplet evaporation was considered. Droplets can be categorized into small droplets (initial size ≤30 μm or ≤10 μm as droplet nuclei), medium droplets (30–80 μm) and large droplets (>100 μm) according to the exposure characteristics. Droplets up to 100 μm, particular the small ones, can contribute to both short-range and long-range airborne routes. For the face-to-face talking scenario, the intake fraction and deposition fractions of droplets on the face and facial mucosa of the susceptible were up to 4.96%, 2.14%, and 0.12%, respectively, indicating inhalation is the dominant route. The exposure risk from a talking infector decreases monotonically with the interpersonal distance, while that of nasal-breathing generated droplets maintains a relatively stable level within 1.0 m. Keeping an angle of 15° or above with the expiratory flow is efficient to reduce intake fractions to <0.37% for small droplets. Adjusting the orientation from face-to-face to face-to-back can reduce exposure to small droplets by approximately 88.0% during talking and 66.2% during breathing. A higher ventilation rate can reduce the risk of exposure to small droplets but may increase the risk of transmission via medium droplets by enhancing their evaporation rate. This study would serve as a fundamental research for epidemiologist, healthcare workers and the public in the purpose of infection control. © 2023 Elsevier Ltd

11.
Journal of Infection and Chemotherapy ; 29(1):102-104, 2023.
Article in English | Scopus | ID: covidwho-2243676

ABSTRACT

During the coronavirus disease 2019 (COVID-19) pandemic, maintaining adequate staffing in healthcare facilities is important to provide a safe work environment for healthcare workers (HCWs). Japan's early return-to-work (RTW) program may be a rational strategy at a time when there is an increased demand for the services of HCWs. We assessed whether the early RTW program for HCWs who have been in close contact with a COVID-19 case in our hospital was justified. Close contacts were identified according to the guidance document of the World Health Organization. HCWs who met all of the following conditions were eligible to apply to an early RTW program: (1) difficult to replace with another HCW, (2) received the third dose of a COVID-19 mRNA vaccine, (3) a negative COVID-19 antigen test before each work shift, and (4) consent from relevant HCWs and their managers to participate in the program. Between January and March 2022, 256 HCWs were identified as close contacts (median age, 35 years;192 female). Thirty-seven (14%) secondary attack cases of COVID-19 were detected. Among 141 HCWs (55%) who applied to the early RTW program, nurses and physicians comprised about three-quarters of participants, with a higher participation rate by physicians (78%) than nurses (59%). Eighteen HCWs tested positive for COVID-19 by the sixth day after starting the early RTW program. No COVID-19 infection clusters were reported during the observation period. These findings suggest that the early RTW program for COVID-19 close contacts was a reasonable strategy for HCWs during the Omicron wave. © 2022 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases

12.
J Med Syst ; 47(1): 24, 2023 Feb 14.
Article in English | MEDLINE | ID: covidwho-2245008

ABSTRACT

Singapore, like many other nations globally, had to contend with significant caseloads arising from the Coronavirus disease (COVID-19) pandemic. This paper focuses on using technology as an intervention for pandemic management. With scant scientific evidence on effective medications and vaccinations (i.e., pharmaceutical interventions) initially, disease containment strategies predominated during the early phases. Non-pharmaceutical interventions were critical in slowing disease transmission and preventing public healthcare institutions from being overwhelmed. Such interventions could be broadly divided into case-based interventions (e.g., contact tracing and quarantining of close contacts) and population-based measures (e.g., mask use and social distancing). The paper describes Singapore's experience in the operational implementation of contact-based interventions, and illustrates how harnessing the digital edge enabled fast, accurate, resource-efficient, and flexible execution of ground operations. Singapore applied digital technology and developed an integrated system to facilitate issuance and acknowledgement of quarantine orders, submission of COVID-19 test results, and collection of antigen rapid test kits at the population level. Data was obtained from this proprietary centralised, automated platform. The paper demonstrates how such simple, yet elegant systems could have a direct impact on disease transmission in an outbreak setting and on population health. Moving forward, it is recommended that technology and digital solutions feature prominently in work process designs beyond COVID-19 such as in the management of emerging infectious diseases and non-communicable diseases.


Subject(s)
COVID-19 , Humans , COVID-19/epidemiology , COVID-19/prevention & control , Quarantine , Contact Tracing/methods , SARS-CoV-2 , Disease Outbreaks/prevention & control
13.
J Infect Public Health ; 16(3): 410-417, 2023 Mar.
Article in English | MEDLINE | ID: covidwho-2210868

ABSTRACT

BACKGROUND: COVID-19 vaccination was expected to reduce SARS-CoV-2 transmission, but the relevance of this effect remains unclear. We aimed to estimate the effectiveness of COVID-19 vaccination of the index cases and their close contacts in reducing the probability of SARS-CoV-2 transmission. METHODS: Transmission of SARS-CoV-2 infection was evaluated in two cohorts of adult close contacts of COVID-19 confirmed cases (social and household settings) by COVID-19 vaccination status of the index case and the close contact, from April to November 2021 in Navarre, Spain. The effects of vaccination of the index case and the close contact were estimated as (1-adjusted relative risk) × 100%. RESULTS: Among 19,631 social contacts, 3257 (17%) were confirmed with SARS-CoV-2. COVID-19 vaccination of the index case reduced infectiousness by 44% (95% CI, 27-57%), vaccination of the close contact reduced susceptibility by 69% (95% CI, 65-73%), and vaccination of both reduced transmissibility by 74% (95% CI, 70-78%) in social settings, suggesting some synergy of effects. Among 20,708 household contacts, 6269 (30%) were infected, and vaccine effectiveness estimates were 13% (95% CI, -5% to 28%), 61% (95% CI, 58-64%), and 52% (95% CI, 47-56%), respectively. These estimates were lower in older people and had not relevant differences between the Alpha (April-June) and Delta (July-November) variant periods. CONCLUSIONS: COVID-19 vaccination reduces infectiousness and susceptibility; however, these effects are insufficient for complete control of SARS-CoV-2 transmission, especially in older people and household setting. Relaxation of preventive behaviors after vaccination may counteract part of the vaccine effect on transmission.


Subject(s)
COVID-19 , SARS-CoV-2 , Adult , Humans , Aged , Cohort Studies , COVID-19/prevention & control , COVID-19 Vaccines , Vaccination
14.
JMIR Public Health Surveill ; 7(6): e27189, 2021 06 03.
Article in English | MEDLINE | ID: covidwho-2197904

ABSTRACT

BACKGROUND: During the COVID-19 pandemic, swab tests proved to be effective in containing the infection and served as a means for early diagnosis and contact tracing. However, little evidence exists regarding the correct timing for the execution of the swab test, especially for asymptomatic individuals and health care workers. OBJECTIVE: The objective of this study was to analyze changes in the positive findings over time in individual SARS-CoV-2 swab tests during a health surveillance program. METHODS: The study was conducted with 2071 health care workers at the University Hospital of Verona, with a known date of close contact with a patient with COVID-19, between February 29 and April 17, 2020. The health care workers underwent a health surveillance program with repeated swab tests to track their virological status. A generalized additive mixed model was used to investigate how the probability of a positive test result changes over time since the last known date of close contact, in an overall sample of individuals who tested positive for COVID-19 and in a subset of individuals with an initial negative swab test finding before being proven positive, to assess different surveillance time intervals. RESULTS: Among the 2071 health care workers in this study, 191 (9.2%) tested positive for COVID-19, and 103 (54%) were asymptomatic with no differences based on sex or age. Among 49 (25.7%) cases, the initial swab test yielded negative findings after close contact with a patient with COVID-19. Sex, age, symptoms, and the time of sampling were not different between individuals with an initial negative swab test finding and those who initially tested positive after close contact. In the overall sample, the estimated probability of testing positive was 0.74 on day 1 after close contact, which increased to 0.77 between days 5 and 8. In the 3 different scenarios for scheduled repeated testing intervals (3, 5, and 7 days) in the subgroup of individuals with an initially negative swab test finding, the probability peaked on the sixth, ninth and tenth, and 13th and 14th days, respectively. CONCLUSIONS: Swab tests can initially yield false-negative outcomes. The probability of testing positive increases from day 1, peaking between days 5 and 8 after close contact with a patient with COVID-19. Early testing, especially in this final time window, is recommended together with a health surveillance program scheduled in close intervals.


Subject(s)
COVID-19 Nucleic Acid Testing/statistics & numerical data , COVID-19/diagnosis , Health Personnel/statistics & numerical data , Adult , COVID-19/epidemiology , COVID-19/transmission , Contact Tracing/methods , False Negative Reactions , Female , Humans , Infectious Disease Transmission, Patient-to-Professional/statistics & numerical data , Italy/epidemiology , Male , Middle Aged , Pandemics , SARS-CoV-2 , Time Factors
15.
14th International Conference on Ubiquitous Computing and Ambient Intelligence, UCAmI 2022 ; 594 LNNS:209-220, 2023.
Article in English | Scopus | ID: covidwho-2173796

ABSTRACT

As a result of the COVID-19 pandemic, public transport systems suffered a significant reduction in passengers due to the suppression of services and reduced vehicle capacity. This reduction jeopardized their role as facilitators of sustainable mobility, causing large economic losses to public transport operators. Therefore, an intelligent management aimed at reducing the risk of contagion among its users is an aspect of interest for public transport operators and a challenge from a scientific point of view. This paper presents the results of a study aimed at analyzing the effect of different seat allocation strategies on the risk of contagion among passengers. Starting from a formalization of the problem based on epidemiological and public transport entities, the methodology employed, based on Data Mining, makes use of simulation processes to analyze the effect of these strategies. The paper presents the results obtained by analyzing a route of a public road passenger transport operator. The results allow us to evaluate the risk of contagion of different seat allocation strategies and to evaluate how this risk varies according to the number of passengers who have traveled on a vehicle journey. © 2023, The Author(s), under exclusive license to Springer Nature Switzerland AG.

16.
Journal of Hazardous Materials ; Part A. 444 (no pagination), 2023.
Article in English | EMBASE | ID: covidwho-2170572

ABSTRACT

People constantly move their heads during conversation, as such movement is an important non-verbal mode of communication. Head movement alters the direction of people's expired air flow, therefore affecting their conversational partners' level of exposure. Nevertheless, there is a lack of understanding of the mechanism whereby head movement affects people's exposure. In this study, a dynamic meshing method in computational fluid dynamics was used to simulate the head movement of a human-shaped thermal manikin. Droplets were released during the oral expiration periods of the source manikin, during which it was either motionless, was shaking its head or was nodding its head, while the head of a face-to-face target manikin remained motionless. The results indicate that the target manikin had a high level of exposure to respiratory droplets when the source manikin was motionless, whereas the target manikin's level of exposure was significantly reduced when the source manikin was shaking or nodding its head. The source manikin had the highest level of self-exposure when it was nodding its head and the lowest level of self-exposure when its head was motionless. People's level of exposure during close contact is highly variable, highlighting the need for further investigations in more realistic conversational scenarios. Copyright © 2022 Elsevier B.V.

17.
Infect Dis Model ; 8(1): 159-171, 2023 Mar.
Article in English | MEDLINE | ID: covidwho-2165358

ABSTRACT

Normalized interventions were implemented in different cities in China to contain the outbreak of COVID-19 before December 2022. However, the differences in the intensity and timeliness of the implementations lead to differences in final size of the infections. Taking the outbreak of COVID-19 in three representative cities Xi'an, Zhengzhou and Yuzhou in January 2022, as examples, we develop a compartmental model to describe the spread of novel coronavirus and implementation of interventions to assess concretely the effectiveness of Chinese interventions and explore their impact on epidemic patterns. After applying reported human confirmed cases to verify the rationality of the model, we apply the model to speculate transmission trend and length of concealed period at the initial spread phase of the epidemic (they are estimated as 10.5, 7.8, 8.2 days, respectively), to estimate the range of basic reproduction number (2.9, 0.7, 1.6), and to define two indexes (transmission rate v t and controlled rate v c ) to evaluate the overall effect of the interventions. It is shown that for Zhengzhou, v c is always more than v t with regular interventions, and Xi'an take 8 days to achieve v c  > v t twice as long as Yuzhou, which can interpret the fact that the epidemic situation in Xi'an was more severe. By carrying out parameter values, it is concluded that in the early stage, strengthening the precision of close contact tracking and frequency of large-scale nucleic acid testing of non-quarantined population are the most effective on controlling the outbreaks and reducing final size. And, if the close contact tracking strategy is sufficiently implemented, at the late stage large-scale nucleic acid testing of non-quarantined population is not essential.

18.
Building and Environment ; 229:109973, 2023.
Article in English | ScienceDirect | ID: covidwho-2165124

ABSTRACT

To quantify the risk of the transmission of respiratory infections in indoor environments, we systematically assessed exposure to talking- and breathing-generated respiratory droplets in a generic indoor environment using computational fluid dynamic (CFD) simulations. The flow field in the indoor environment was obtained with SST k-ω model and Lagrangian method was used to predict droplet trajectories, where droplet evaporation was considered. Droplets can be categorized into small droplets (initial size ≤30 μm or ≤10 μm as droplet nuclei), medium droplets (30–80 μm) and large droplets (>100 μm) according to the exposure characteristics. Droplets up to 100 μm, particular the small ones, can contribute to both short-range and long-range airborne routes. For the face-to-face talking scenario, the intake fraction and deposition fractions of droplets on the face and facial mucosa of the susceptible were up to 4.96%, 2.14%, and 0.12%, respectively, indicating inhalation is the dominant route. The exposure risk from a talking infector decreases monotonically with the interpersonal distance, while that of nasal-breathing generated droplets maintains a relatively stable level within 1.0 m. Keeping an angle of 15° or above with the expiratory flow is efficient to reduce intake fractions to <0.37% for small droplets. Adjusting the orientation from face-to-face to face-to-back can reduce exposure to small droplets by approximately 88.0% during talking and 66.2% during breathing. A higher ventilation rate can reduce the risk of exposure to small droplets but may increase the risk of transmission via medium droplets by enhancing their evaporation rate. This study would serve as a fundamental research for epidemiologist, healthcare workers and the public in the purpose of infection control.

19.
Bali Medical Journal ; 11(3):1614-1619, 2022.
Article in English | Web of Science | ID: covidwho-2155886

ABSTRACT

Introduction: Several countries, including Indonesia, have made tracing efforts to control the spread of infectious diseases such as COVID-19. In carrying out this tracing, it is not only about tracing close contacts but also about digging up some information related to the epidemiological characteristics of COVID-19. So this information can be useful in analyzing the future incidence of disease or health problems. This paper aims to analyze the management of tracing and epidemiological characteristics of close contacts with COVID-19 in Primary Health Care (Puskesmas). Especially Primary Health Care in Pengasih I, Pengasih II, Sentolo I, and Sentolo II.Methods: The design of this study is a type of descriptive epidemiological research with retrospective data. Retrospective data were analyzed descriptively regarding the epidemiological characteristics of close contact with COVID-19. They then tested the formulation of the hypothesis with univariate, bivariate, and multivariate data analysis. Total sampling was utilized for the study from February 1(st) to March 3(rd,) 2022.Results: Contact tracing was carried out by following the guidelines for tracing implementation issued by the government. Close contact data is 1,450 and dominated by women aged 16-54. The frequency of asymptomatic is more than that of symptomatic. There are 535 close contacts whose status changed to confirmed cases.Conclusion: Close contacts have the risk of undetected infection, so early control of close contact can control the spread of the COVID-19 outbreak. Therefore, tracing efforts by health workers aimed at early detection of close contacts and quarantine measures for close household contacts are appropriate to break the chain of transmission of COVID-19 so that this tracing can be achieved.

20.
China Journal of Leprosy and Skin Diseases ; 38(12):767-768, 2022.
Article in Chinese | Scopus | ID: covidwho-2145259

ABSTRACT

Background: April 11 , 2022, we learned from the public information platform that a COVID-19 close contact was tested nucleic acid in our hospital recently. This survey was performed to verify the infor-mation and timely identify high risk population of COVID 19. Methods: According to the National COVID-19 Control and Prevention Protocol ( 8th edition) , and the Emergency Response Plan for COVID-19 in our hospital, information verification, close contact investigation, indirect contact tracing, information report and close contact follow up were carried out by our team. Results: A total of 40 indirect contacts were identified. The basic information of those 40 indirect contacts was reported to the local Center for Diseases Control and Prevention. The close contact was followed up for 10 days, and the nucleic acid test results of COVID-19 of the contact were negative since then. No fever or other suspected symptoms of COVID-19 were appeared for the contact. Conclusion: Timely verify the COVID-19 related information, screening of high risk population and dynamically monitoring of the close contact will help to control the potential spread of COVID 19. 767. © 2022 Colegio Brasileiro de Patologia Animal. All rights reserved.

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